The Anti-beta-Actin antibody (monoclonal) from MyBioSource.com is a Mouse Monoclonal antibody to Actb, Actin, beta, and Beta-Actin. This antibody recognizes Human, Mouse, and Rat antigen. The Anti-beta-Actin antibody (monoclonal) has been validated for the following applications: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Description: Mouse IgG monoclonal antibody for beta-Actin, actin, beta (ACTB) detection. Tested with WB, IHC-P in Human, mouse, rat. No cross reactivity with other proteins. Uniprot ID: P60709
Background: The primary site of action of cytochalasin B on cell motility processes is beta-actin. Habets et al.(1992) generated hybrids that harbor only specific regions of human chromosome 7 and assigned the ACTB locus to 7p15-p12. ACTB and the other assigned beta-actin-related sequences are dispersed over at least four different chromosomes including one locus assigned to the X chromosome. A mutation of beta-actin that alters depolymerization dynamics is associated with autosomal dominant developmental malformations, deafness, and dystonia